Publications

Publications

Select Publications

Sheng, W, Harden, SW, Tan, Y, Krause, EG, Frazier, CJ. Dendritic osmosensors modulate activity-induced calcium influx in oxytocinergic magnocellular neurons of the mouse PVN. Elife. 2021;10 :. doi: 10.7554/eLife.63486. PubMed PMID:34250900 .

Endogenous oxytocin inhibits hypothalamic CRH neurons following acute hypernatremia. Pati D, Harden SW, Sheng W, Kelly KB, Kloet AD, Krause EG, Frazier CJ. 2020. Journal of Neuroendocrinology PMID 32133707

Oxytocin Receptors Are Expressed by Glutamatergic Prefrontal Cortical Neurons That Selectively Modulate Social Recognition. Tan,Y, Singhal SM, Harden SW, Cahill KM, Nguyen DM, Colon-Perez LM, Sahagian TJ, Thinschmidt JS, de Kloet AD, Febo M, Frazier CJ, Krause EG. 2019 J Neurosci. 39(17):3249–3263. PMID 30804095

Oxytocin depolarizes fast-spiking hilar interneurons and induces GABA release onto mossy cells of the rat dentate gyrus. Harden SW, Frazier CJ. Hippocampus. 2016; 26(9):1124-39. PMID 27068005 and cover

McQuail, JA, Beas, BS, Kelly, KB, Simpson, KL, Frazier, CJ, Setlow, B, Bizon, JL. NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.J. Neurosci. 2016;36 (50):12537-12548. doi: 10.1523/JNEUROSCI.2332-16.2016. PubMed PMID:27807032 PubMed Central PMC5157101.

Carpenter, HE, Kelly, KB, Bizon, JL, Frazier, CJ. Age-related changes in tonic activation of presynaptic versus extrasynaptic γ-amniobutyric acid type B receptors in rat medial prefrontal cortex.Neurobiol. Aging. 2016;45 :88-97. doi: 10.1016/j.neurobiolaging.2016.05.015. PubMed PMID:27459929 PubMed Central PMC5235322.

 

Recent Publications

Pyon, WS, Viera-Resto, OA, Faraji, M, Blaes, SL, Orsini, CA, Gotlin, MS, Raptis, C, Cruz-Wegener, C, Behnood-Rod, A, Hellbusch, BM, Joseph, SW, Barrett, J, Holik, HM, Singhal, SM, Burns, MR, Frazier, CJ, Bizon, JL, Setlow, B. Ventral tegmental area dopamine neuron activity mediates multi-valent outcomes during decision making under risk of punishment. bioRxiv. 2026; :. doi: 10.64898/2026.07.14.738459. PubMed PMID:42539269 PubMed Central PMC13419817.

Faraji, M, Hernandez, CM, Wheeler, AR, Sahagian, TJ, Harden, SW, Frazier, CJ, Burns, MR, Setlow, B, Bizon, JL. Optogenetic inhibition reveals distinct contributions of medial prefrontal cortex to intertemporal choice in young and aged rats. Cereb Cortex. 2025;35 (10):. doi: 10.1093/cercor/bhaf288. PubMed PMID:41092052 PubMed Central PMC12527352.

Faraji, M, Hernandez, CM, Wheeler, AR, Sahagian, TJ, Harden, SW, Frazier, CJ, Burns, MR, Setlow, B, Bizon, JL. Optogenetic inhibition reveals distinct contributions of medial prefrontal cortex to intertemporal choice in young and aged rats. bioRxiv. 2025; :. doi: 10.1101/2025.07.15.664949. PubMed PMID:40791560 PubMed Central PMC12338721.

Sahagian, TJ, Harden, SW, Bizon, JL, Setlow, B, Frazier, CJ. Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala. Front Cell Neurosci. 2025;19 :1634594. doi: 10.3389/fncel.2025.1634594. PubMed PMID:40746495 PubMed Central PMC12310679.

Sahagian, TJ, Harden, SW, Bizon, JL, Setlow, B, Frazier, CJ. Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala. bioRxiv. 2025; :. doi: 10.1101/2025.03.14.643393. PubMed PMID:40161757 PubMed Central PMC11952550.

Härer, A, Frazier, CJ, Rennison, DJ. Host ecotype and rearing environment are the main drivers of threespine stickleback gut microbiota diversity in a naturalistic experiment. R Soc Open Sci. 2024;11 (6):240649. doi: 10.1098/rsos.240649. PubMed PMID:39100190 PubMed Central PMC11296155.

Baumer-Harrison, C, Elsaafien, K, Johnson, DN, Peñaloza Aponte, JD, de Araujo, A, Patel, S, Bruce, EB, Harden, SW, Frazier, CJ, Scott, KA, de Lartigue, G, Krause, EG, de Kloet, AD. Alleviating Hypertension by Selectively Targeting Angiotensin Receptor-Expressing Vagal Sensory Neurons. J Neurosci. 2024;44 (9):. doi: 10.1523/JNEUROSCI.1154-23.2023. PubMed PMID:38242697 PubMed Central PMC10904025.

Frazier, CJG, Gokool, VA, Holness, HK, Mills, DK, Furton, KG. Multivariate regression modelling for gender prediction using volatile organic compounds from hand odor profiles via HS-SPME-GC-MS. PLoS One. 2023;18 (7):e0286452. doi: 10.1371/journal.pone.0286452. PubMed PMID:37405979 PubMed Central PMC10321641.

Truckenbrod, LM, Betzhold, SM, Wheeler, AR, Shallcross, J, Singhal, S, Harden, S, Schwendt, M, Frazier, CJ, Bizon, JL, Setlow, B, Orsini, CA. Circuit and Cell-Specific Contributions to Decision Making Involving Risk of Explicit Punishment in Male and Female Rats. J Neurosci. 2023;43 (26):4837-4855. doi: 10.1523/JNEUROSCI.0276-23.2023. PubMed PMID:37286352 PubMed Central PMC10312052.

Truckenbrod, LM, Betzhold, SM, Wheeler, AR, Shallcross, J, Singhal, S, Harden, S, Schwendt, M, Frazier, CJ, Bizon, JL, Setlow, B, Orsini, CA. Circuit and cell-specific contributions to decision making involving risk of explicit punishment in male and female rats. bioRxiv. 2023; :. doi: 10.1101/2023.01.15.524142. PubMed PMID:36711946 PubMed Central PMC9882127.

Pati, D, Krause, EG, Frazier, CJ. Intrahypothalamic effects of oxytocin on PVN CRH neurons in response to acute stress. Curr Opin Endocr Metab Res. 2022;26 :. doi: 10.1016/j.coemr.2022.100382. PubMed PMID:36618014 PubMed Central PMC9815561.

Thinschmidt, JS, Harden, SW, King, MA, Talton, JD, Frazier, CJ. A rapid in vitro assay for evaluating the effects of acetylcholinesterase inhibitors and reactivators in the rat basolateral amygdala. Front Cell Neurosci. 2022;16 :1066312. doi: 10.3389/fncel.2022.1066312. PubMed PMID:36479275 PubMed Central PMC9721344.

Elsaafien, K, Harden, SW, Johnson, DN, Kimball, AK, Sheng, W, Smith, JA, Scott, KA, Frazier, CJ, de Kloet, AD, Krause, EG. A Novel Organ-Specific Approach to Selectively Target Sensory Afferents Innervating the Aortic Arch. Front Physiol. 2022;13 :841078. doi: 10.3389/fphys.2022.841078. PubMed PMID:35399269 PubMed Central PMC8987286.

McQuail, JA, Beas, BS, Kelly, KB, Hernandez, CM 3rd, Bizon, JL, Frazier, CJ. Attenuated NMDAR signaling on fast-spiking interneurons in prefrontal cortex contributes to age-related decline of cognitive flexibility. Neuropharmacology. 2021;197 :108720. doi: 10.1016/j.neuropharm.2021.108720. PubMed PMID:34273386 PubMed Central PMC8478839.Search PubMed