Select Publications

Sheng, W, Harden, SW, Tan, Y, Krause, EG, Frazier, CJ. Dendritic osmosensors modulate activity-induced calcium influx in oxytocinergic magnocellular neurons of the mouse PVN. Elife. 2021;10 :. doi: 10.7554/eLife.63486. PubMed PMID:34250900 .

Endogenous oxytocin inhibits hypothalamic CRH neurons following acute hypernatremia. Pati D, Harden SW, Sheng W, Kelly KB, Kloet AD, Krause EG, Frazier CJ. 2020. Journal of Neuroendocrinology PMID 32133707

Oxytocin Receptors Are Expressed by Glutamatergic Prefrontal Cortical Neurons That Selectively Modulate Social Recognition. Tan,Y, Singhal SM, Harden SW, Cahill KM, Nguyen DM, Colon-Perez LM, Sahagian TJ, Thinschmidt JS, de Kloet AD, Febo M, Frazier CJ, Krause EG. 2019 J Neurosci. 39(17):3249–3263. PMID 30804095

Oxytocin depolarizes fast-spiking hilar interneurons and induces GABA release onto mossy cells of the rat dentate gyrus. Harden SW, Frazier CJ. Hippocampus. 2016; 26(9):1124-39. PMID 27068005 and cover

McQuail, JA, Beas, BS, Kelly, KB, Simpson, KL, Frazier, CJ, Setlow, B, Bizon, JL. NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.J. Neurosci. 2016;36 (50):12537-12548. doi: 10.1523/JNEUROSCI.2332-16.2016. PubMed PMID:27807032 PubMed Central PMC5157101.

Carpenter, HE, Kelly, KB, Bizon, JL, Frazier, CJ. Age-related changes in tonic activation of presynaptic versus extrasynaptic γ-amniobutyric acid type B receptors in rat medial prefrontal cortex.Neurobiol. Aging. 2016;45 :88-97. doi: 10.1016/j.neurobiolaging.2016.05.015. PubMed PMID:27459929 PubMed Central PMC5235322.


Recent Publications

Baumer-Harrison, C, Elsaafien, K, Johnson, DN, Peñaloza Aponte, JD, de Araujo, A, Patel, S, Bruce, EB, Harden, SW, Frazier, CJ, Scott, KA, de Lartigue, G, Krause, EG, de Kloet, AD. Alleviating Hypertension by Selectively Targeting Angiotensin Receptor-Expressing Vagal Sensory Neurons. J Neurosci. 2024;44 (9):. doi: 10.1523/JNEUROSCI.1154-23.2023. PubMed PMID:38242697 PubMed Central PMC10904025.

Frazier, CJG, Gokool, VA, Holness, HK, Mills, DK, Furton, KG. Multivariate regression modelling for gender prediction using volatile organic compounds from hand odor profiles via HS-SPME-GC-MS. PLoS One. 2023;18 (7):e0286452. doi: 10.1371/journal.pone.0286452. PubMed PMID:37405979 PubMed Central PMC10321641.

Truckenbrod, LM, Betzhold, SM, Wheeler, AR, Shallcross, J, Singhal, S, Harden, S, Schwendt, M, Frazier, CJ, Bizon, JL, Setlow, B, Orsini, CA. Circuit and Cell-Specific Contributions to Decision Making Involving Risk of Explicit Punishment in Male and Female Rats. J Neurosci. 2023;43 (26):4837-4855. doi: 10.1523/JNEUROSCI.0276-23.2023. PubMed PMID:37286352 PubMed Central PMC10312052.

Truckenbrod, LM, Betzhold, SM, Wheeler, AR, Shallcross, J, Singhal, S, Harden, S, Schwendt, M, Frazier, CJ, Bizon, JL, Setlow, B, Orsini, CA. Circuit and cell-specific contributions to decision making involving risk of explicit punishment in male and female rats. bioRxiv. 2023; :. doi: 10.1101/2023.01.15.524142. PubMed PMID:36711946 PubMed Central PMC9882127.

Pati, D, Krause, EG, Frazier, CJ. Intrahypothalamic effects of oxytocin on PVN CRH neurons in response to acute stress. Curr Opin Endocr Metab Res. 2022;26 :. doi: 10.1016/j.coemr.2022.100382. PubMed PMID:36618014 PubMed Central PMC9815561.

Thinschmidt, JS, Harden, SW, King, MA, Talton, JD, Frazier, CJ. A rapid in vitro assay for evaluating the effects of acetylcholinesterase inhibitors and reactivators in the rat basolateral amygdala. Front Cell Neurosci. 2022;16 :1066312. doi: 10.3389/fncel.2022.1066312. PubMed PMID:36479275 PubMed Central PMC9721344.

Elsaafien, K, Harden, SW, Johnson, DN, Kimball, AK, Sheng, W, Smith, JA, Scott, KA, Frazier, CJ, de Kloet, AD, Krause, EG. A Novel Organ-Specific Approach to Selectively Target Sensory Afferents Innervating the Aortic Arch. Front Physiol. 2022;13 :841078. doi: 10.3389/fphys.2022.841078. PubMed PMID:35399269 PubMed Central PMC8987286.

McQuail, JA, Beas, BS, Kelly, KB, Hernandez, CM 3rd, Bizon, JL, Frazier, CJ. Attenuated NMDAR signaling on fast-spiking interneurons in prefrontal cortex contributes to age-related decline of cognitive flexibility. Neuropharmacology. 2021;197 :108720. doi: 10.1016/j.neuropharm.2021.108720. PubMed PMID:34273386 PubMed Central PMC8478839.

Sheng, W, Harden, SW, Tan, Y, Krause, EG, Frazier, CJ. Dendritic osmosensors modulate activity-induced calcium influx in oxytocinergic magnocellular neurons of the mouse PVN. Elife. 2021;10 :. doi: 10.7554/eLife.63486. PubMed PMID:34250900 PubMed Central PMC8457833.

Liu, Y, Xing, H, Sheng, W, Singh, KN, Korkmaz, AG, Comeau, C, Anika, M, Ernst, A, Yokoi, F, Vaillancourt, DE, Frazier, CJ, Li, Y. Alteration of the cholinergic system and motor deficits in cholinergic neuron-specific Dyt1 knockout mice. Neurobiol Dis. 2021;154 :105342. doi: 10.1016/j.nbd.2021.105342. PubMed PMID:33757902 PubMed Central PMC8113083.

Mohammed, M, Johnson, DN, Wang, LA, Harden, SW, Sheng, W, Spector, EA, Elsaafien, K, Bader, M, Steckelings, UM, Scott, KA, Frazier, CJ, Sumners, C, Krause, EG, de Kloet, AD. Targeting angiotensin type-2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice. Cardiovasc Res. 2022;118 (3):883-896. doi: 10.1093/cvr/cvab085. PubMed PMID:33723600 PubMed Central PMC9020199.

Frazier, CJ, Harden, SW, Alleyne, AR, Mohammed, M, Sheng, W, Smith, JA, Elsaafien, K, Spector, EA, Johnson, DN, Scott, KA, Krause, EG, de Kloet, AD. An Angiotensin-Responsive Connection from the Lamina Terminalis to the Paraventricular Nucleus of the Hypothalamus Evokes Vasopressin Secretion to Increase Blood Pressure in Mice. J Neurosci. 2021;41 (7):1429-1442. doi: 10.1523/JNEUROSCI.1600-20.2020. PubMed PMID:33328294 PubMed Central PMC7896018.

Pati, D, Harden, SW, Sheng, W, Kelly, KB, de Kloet, AD, Krause, EG, Frazier, CJ. Endogenous oxytocin inhibits hypothalamic corticotrophin-releasing hormone neurones following acute hypernatraemia. J Neuroendocrinol. 2020;32 (3):e12839. doi: 10.1111/jne.12839. PubMed PMID:32133707 PubMed Central PMC7384450.

Cirino, TJ, Harden, SW, McLaughlin, JP, Frazier, CJ. Region-specific effects of HIV-1 Tat on intrinsic electrophysiological properties of pyramidal neurons in mouse prefrontal cortex and hippocampus. J Neurophysiol. 2020;123 (4):1332-1341. doi: 10.1152/jn.00029.2020. PubMed PMID:32101482 PubMed Central PMC7191522.Search PubMed